CLCNKB (N-term) Rabbit Polyclonal Antibody

CAT#: AP50941PU-N

CLCNKB (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

CLCNKB Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the CLCNKB antibody detected the CLCNKB protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 10-40 amino acids from the N-terminal region of human CLCNKB
• Specificity: This antibody reacts to CLCNKB.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 75446 Da
• Gene Name: Homo sapiens chloride voltage-gated channel Kb (CLCNKB), transcript variant 1
• Database Link:
  Entrez Gene 56365 MouseEntrez Gene 1188 Human
• Background: The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
• Synonyms: Chloride channel protein ClC-Kb, Chloride channel Kb, ClC-K2, ClCK2

Reference Data

• Protein Families: Druggable Genome, Transmembrane