Corticotropin Releasing Factor (CRH) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51081PU-N

Corticotropin Releasing Factor (CRH) (C-term) rabbit polyclonal antibody, Aff - Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

Product Images

Specifications

Product Data
Applications WB
Recommended Dilution ELISA: 1/1000.
Western Blot: 1/100-1/500.
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Specificity This antibody recognizes Human Corticoliberin (C-term).
Formulation PBS
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Gene Name Homo sapiens corticotropin releasing hormone (CRH)
Background
Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.
Synonyms CRF, CRH, Corticotropin-Releasing Hormone, Corticotropin-Releasing Factor
Note Molecular Weight: 21422 Da
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Long-term depression

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.