DKK1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP51269PU-N

DKK1 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Dickkopf-1 Antibody (N-term) in T47D cell line lysates (35ug/lane). DKK1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 64~93 amino acids from the N-terminal region of Human Dickkopf-1.
• Specificity: This antibody recognizes Human Dickkopf-1 (N-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens dickkopf WNT signaling pathway inhibitor 1 (DKK1)
• Database Link:
  Entrez Gene 22943 Human
• Background: DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
• Synonyms: DKK1, DKK-1, Dickkopf-related protein 1, SK
• Note: Molecular Weight: 28672 Da

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway
• Protein Pathways: Wnt signaling pathway