DLK (DLK1) Rabbit Polyclonal Antibody

CAT#: AP51272PU-N

DLK (DLK1) rabbit polyclonal antibody, Aff - Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

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Other products for "DLK1"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution

Immunohistochemistry on Paraffin Sections: 1/50-1/100.
Western blot: 1/1000.
Enzyme immunoassay: 1/1000.

Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen Recombinant protein of Human DLK
Specificity This antibody recognizes Human DLK1.
Other species not tested.
Formulation PBS with 0.09% (W/V) Sodium Azide
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified through a Protein A column followed by peptide affinity purification
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Gene Name Homo sapiens delta-like 1 homolog (Drosophila) (DLK1), transcript variant 1
Background This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
Synonyms DLK-1, DLK, Protein delta homolog 1, pG2, PREF1, Preadipocyte factor 1
Note Molecular Weight: 41300 Da
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.