OVCA1 (DPH1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51311PU-N

OVCA1 (DPH1) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of DPH1 / OVAC1 Antibody (C-term) in A375 cell line lysates (35ug/lane). This demonstrates the DPH1 antibody detected the DPH1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 383-412 amino acids from the C-terminal region of Human DPH1
• Specificity: This antibody recognizes Human DPH1 / OVAC1 (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens diphthamide biosynthesis 1 (DPH1)
• Database Link:
  Entrez Gene 1801 Human
• Background: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]). [supplied by OMIM].
• Synonyms: DPH2L, DPH2L1
• Note: Molecular Weight: 48805 Da