eIF3s8 (EIF3C) (Center) Rabbit Polyclonal Antibody

CAT#: AP51395PU-N

eIF3s8 (EIF3C) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

EIF3C Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the EIF3C antibody detected the EIF3C protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 537-567 amino acids from the Central region of human EIF3C
• Specificity: This antibody reacts to EIF3C.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 105344 Da
• Gene Name: Homo sapiens eukaryotic translation initiation factor 3 subunit C (EIF3C), transcript variant 2
• Database Link:
  Entrez Gene 56347 MouseEntrez Gene 8663 Human
• Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
• Synonyms: Eukaryotic translation initiation factor 3 subunit C, eIF3 p110

Reference Data

• Protein Families: Druggable Genome