FGL1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51664PU-N

FGL1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in MDA-MB435 cell line lysates (35ug/lane) using FGL1 antibody. (C-term).This demonstrates the FGL1 antibody detected the FGL1 protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded (FFPE) human liver tissue using FGL1 antibody. (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FGL1 antibody for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: This antibody is suitable for Immunohistochemistry on paraffin sections and Western blotting.
  The suggested dilution is:
  Immunohistochemistry on paraffin sections: 1/10-1/50
  Western blotting: 1/100-1/500
  
  
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide from the C-terminal region ( between 225-256 aa) of human FGL1.
• Specificity: This antibody detects Human FGL1 at C-terminal region.
• Formulation: PBS with 0.09% (W/V) Sodium Azide.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column; followed by peptide affinity purification.
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens fibrinogen like 1 (FGL1), transcript variant 1
• Database Link:
  Entrez Gene 2267 Human
• Background: Fibrinogen-like 1 is a member of a fibrinogen family. FGL1 is homologous to the carboxy
  terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved
  cysteines of fibrinogens and fibrinogen related proteins. However, FGL1 lacks the
  platelet-binding site, cross-linking region and a thrombin-sensitive site which are
  necessary for fibrin clot formation. FGL1 may play a role in the development of
  hepatocellular carcinomas.
• Synonyms: Fibrinogen-like protein 1, Hepassocin, HP-041, HFREP1, LFIRE1
• Note: Molecular Weight: 36379 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein