Fibromodulin (FMOD) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51689PU-N

Fibromodulin (FMOD) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Fibromodulin Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). FMOD (arrow) was detected using the purified Pab.

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  Formalin-fixed and paraffin-embedded human brain tissue reacted with Fibromodulin Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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  Flow cytometric analysis of Hela cells using Fibromodulin Antibody (C-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 343~373 amino acids from the C-terminal region of Human Fibromodulin.
• Specificity: This antibody recognizes Human and Mouse Fibromodulin (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens fibromodulin (FMOD), transcript variant 1
• Database Link:
  Entrez Gene 14264 MouseEntrez Gene 2331 Human
• Background: Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.
• Synonyms: FMOD, FM, SLRR2E, KSPG fibromodulin
• Note: Molecular Weight: 43179 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein