LOC102723996 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52143PU-N

LOC102723996 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CD275 / ICOS Ligand (C-term) Antibody in HL-60 cell line lysates (35ug/lane). This demonstrates the ICOSLG antibody detected the ICOSLG protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 216-246 amino acids from the C-terminal region of human CD275 / ICOS Ligand
• Specificity: This antibody recognizes Human CD275 / ICOS Ligand (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens inducible T-cell costimulator ligand (ICOSLG), transcript variant 1
• Database Link:
  Entrez Gene 23308 HumanEntrez Gene 102723996 Human
• Background: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
• Synonyms: B7 homolog 2, B7-like protein Gl50, B7-related protein 1, ICOSLG, B7H2, B7RP1, B7RP-1, ICOSL, KIAA0653
• Note: Molecular Weight: 33349 Da

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)