IGSF8 (Center) Rabbit Polyclonal Antibody

CAT#: AP52177PU-N

IGSF8 (Center) rabbit polyclonal antibody, Aff - Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution Immunohistochemistry (Paraffin sections):  1/10-1/50
Western blotting:  1/100-1/500
ELISA:  1/1000
Reactivities Human, Mouse
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen Synthetic peptide (233-262 aa) - KLH conjugated - corresponding to internal domain of human IGSF8.
Specificity This antibody detects IGSF8 (Center).
Formulation PBS with 0.09% (W/V) Sodium Azide.
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified through a protein A column; followed by peptide affinity purification.
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Gene Name Homo sapiens immunoglobulin superfamily, member 8 (IGSF8), transcript variant 2
Background GSF8/PGRL/EWI-2 is a membrane protein that contains 4 Ig domains and forms highly proximal, specific and stoichiometric complexes with both CD9 and CD81 a tetraspanin. Tetraspanins and their molecular partners from primary complexes that then undergo tetraspanin-tetraspanin interactions to form a network of molecular interactions call a tetraspanin web. IGSF8 then may play a key role in diverse functions ascribed to CD81 and CD9 including oocyte fertilization or hepatitis C virus function, regulation of proliferation and differentiation of keratinocytes. It may also be a negative regulator of cell motility and suppress T-cell mobility coordinately with CD81.
Synonyms CD81 partner 3, LIR-D1, CD81P3, EWI2, KCT4
Note Molecular Weight: 65034 Da
Reference Data
Protein Families Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.