KDM4C (C-term) Rabbit Polyclonal Antibody

CAT#: AP52272PU-N

KDM4C (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of JMJD2C Antibody (C-term) in K562 cell line lysates (35ug/lane). This demonstrates the JMJD2C antibody detected the JMJD2C protein (arrow).

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  Flow cytometric analysis of K562 cells usinb JMJD2C Antibody (C-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1030-1056 amino acids from the C-terminal region of human JMJD2C
• Specificity: This antibody recognizes Human JMJD2C / KDM4C (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens lysine (K)-specific demethylase 4C (KDM4C), transcript variant 2
• Database Link:
  Entrez Gene 23081 Human
• Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
• Synonyms: GASC1, JHDM3C, KIAA0780, GASC-1 protein
• Note: Molecular Weight: 119982 Da

Reference Data

• Protein Families: Druggable Genome, Transcription Factors