KIR2.3 (KCNJ4) (N-term) Rabbit Polyclonal Antibody

CAT#: AP52311PU-N

KIR2.3 (KCNJ4) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of KCNJ4 Antibody (N-term) in CEM cell line lysates (35ug/lane). This demonstrates the KCNJ4 antibody detected the KCNJ4 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KCNJ4
• Specificity: This antibody recognizes Human KCNJ4 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens potassium voltage-gated channel subfamily J member 4 (KCNJ4), transcript variant 2
• Database Link:
  Entrez Gene 3761 Human
• Background: Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
• Synonyms: KCNJ4, Inward rectifier K(+) channel Kir2.3, Hippocampal inward rectifier, HIRK2, HRK1, HIR, Inward rectifier potassium channel 4
• Note: Molecular Weight: 49500 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane