LZTS2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52575PU-N

LZTS2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of LZTS2 Antibody (C-term) in WiDr cell line lysates (35ug/lane). This demonstrates the LZTS2 antibody detected the LZTS2 protein (arrow)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 571-601 amino acids from the C-terminal region of human LZTS2
• Specificity: This antibody recognizes Human LZTS2 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens leucine zipper, putative tumor suppressor 2 (LZTS2), transcript variant 1
• Database Link:
  Entrez Gene 84445 Human
• Background: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
• Synonyms: LZTS2, KIAA1813, LAPSER1, Leucine zipper putative tumor suppressor 2, hLZTS2
• Note: Molecular Weight: 72759 Da

Reference Data

• Protein Families: Druggable Genome