OTOP1 (Center) Rabbit Polyclonal Antibody

CAT#: AP53128PU-N

OTOP1 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Otopetrin-1 Antibody (Center) in mouse heart tissue lysates (35ug/lane). This demonstrates the OTOP1 antibody detected the OTOP1 protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue reacted with Otopetrin-1 Antibody (Center), which was peroxidase conjugated to the secondary antibody and followed by DAB staining. This data demonstrates the use of OTOP1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 367-396 amino acids from the Central region of Human Otopetrin-1
• Specificity: This antibody recognizes Human and Mouse Otopetrin-1 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens otopetrin 1 (OTOP1)
• Database Link:
  Entrez Gene 21906 MouseEntrez Gene 133060 Human
• Background: OTOP1 is required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP (By similarity).
• Synonyms: OTOP1
• Note: Molecular Weight: 67353 Da

Reference Data

• Protein Families: Transmembrane