POU3F2 (Center) Rabbit Polyclonal Antibody

CAT#: AP53399PU-N

POU3F2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in K562 cell line lysates (35ug/lane) detecting POU3F2 protein by the use of POU3F2 antibody no.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000
  Western blotting: 1/100 - 1/500
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 198-226 amino acids from the central region of human POU3F2
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens POU class 3 homeobox 2 (POU3F2)
• Database Link:
  Entrez Gene 5454 Human
• Background: POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).
• Synonyms: BRN2, Brain-2, Brn-2, OCT7, Oct-7, OTF7, OTF-7
• Note: Molecular Weight: 46893 Da

Reference Data

• Protein Families: Transcription Factors