Sterol carrier protein 2 (SCP2) (N-term) Rabbit Polyclonal Antibody

CAT#: AP53816PU-N

Sterol carrier protein 2 (SCP2) (N-term) rabbit polyclonal antibody, Aff - Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA: 1/1,000.
Western blotting: 1/100-1/500.
Immunohistochemistry: 1/10-1/50.
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 13-43 amino acids from the N-terminal region of Human SCP2
Specificity Recognizes SCP2 (N-term).
Formulation PBS with 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein A column followed by peptide Affinity purification
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens sterol carrier protein 2 (SCP2), transcript variant 3
Background This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
Synonyms SCP-2, SCP-X, SCP-chi, Sterol carrier protein 2, Sterol carrier protein X, NSL-TP
Note Molecular Weight: 58994 Da
Reference Data
Protein Pathways Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.