Sulfatase 2 (SULF2) (C-term) Rabbit Polyclonal Antibody

CAT#: AP54099PU-N

Sulfatase 2 (SULF2) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

SULF2 Antibody (C-term) western blot analysis in human normal Uterus cell line lysates (35ug/lane).This demonstrates the SULF2 antibody detected the SULF2 protein (arrow).

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  SULF2 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SULF2 antibody detected the SULF2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 831-860 amino acids from the C-terminal region of human SULF2
• Specificity: This antibody reacts to SULF2.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 100455 Da
• Gene Name: Homo sapiens sulfatase 2 (SULF2), transcript variant 3
• Database Link:
  Entrez Gene 72043 MouseEntrez Gene 55959 Human
• Background: Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).
• Synonyms: KIAA1247

Reference Data

• Protein Families: Druggable Genome, Transmembrane