TBX5 (N-term) Rabbit Polyclonal Antibody

CAT#: AP54186PU-N

TBX5 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

TBX5 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TBX5 antibody detected the TBX5 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1/100 - 1/500.
  ELISA: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TBX5
• Specificity: This antibody reacts to TBX5.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 57711 Da
• Gene Name: Homo sapiens T-box 5 (TBX5), transcript variant 1
• Database Link:
  Entrez Gene 6910 Human
• Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.
• Synonyms: T-box protein 5
• Note:
  

Reference Data

• Protein Families: Druggable Genome, Transcription Factors