HOX11 (TLX1) (Center) Rabbit Polyclonal Antibody

CAT#: AP54272PU-N

HOX11 (TLX1) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

TLX1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35 ug/lane). This demonstrates the TLX1 antibody detected the TLX1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human TLX1
• Specificity: This antibody detects TLX1 (Center).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens T-cell leukemia homeobox 1 (TLX1), transcript variant 1
• Database Link:
  Entrez Gene 21908 MouseEntrez Gene 3195 Human
• Background: This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.
• Synonyms: TLX-1, T-cell leukemia homeobox protein 1, HOX11, Hox-11, TCL3, TCL-3
• Note: Molecular Weight: 34365 Da