TTL (C-term) Rabbit Polyclonal Antibody

CAT#: AP54406PU-N

TTL (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

TTL Antibody (C-term) western blot analysis in Ramos cell line lysates (35 ug/lane). This demonstrates the TTL antibody detected the TTL protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 355-385 amino acids from the C-terminal region of human TTL
• Specificity: This antibody detects TTL (C-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens tubulin tyrosine ligase (TTL)
• Database Link:
  Entrez Gene 150465 Human
• Background: TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).
• Synonyms: Tubulin-tyrosine ligase, Tubulin tyrosine ligase
• Note: Molecular Weight: 43212 Da