Smad Interacting Protein 1 (ZEB2) (C-term) Rabbit Polyclonal Antibody

CAT#: AP54642PU-N

Smad Interacting Protein 1 (ZEB2) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

ZEB2 Antibody (C-term) (AP54642PU-N) western blot analysis in MDA-MB435 cell line lysates (35 ug/lane). This demonstrates the ZEB2 antibody detected the ZEB2 protein (arrow).

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  ZEB2 Antibody (C-term) (AP54642PU-N) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
  Flow cytometry: 1:10~50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Immunized with a KLH conjugated synthetic peptide between 1078-1105 amino acids from the C-terminal region of human ZEB2
• Specificity: This antibody detects ZFHX1B (C-term).
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column; followed by peptide affinity purification.
  State: Aff - Purified
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: zinc finger E-box binding homeobox 2
• Database Link:
  Entrez Gene 9839 Human
  UniProt ID O60315
• Background: The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: ZFX1B, ZEB2, SMADIP1, SIP1, KIAA0569
• Note: Molecular Weight: 136447 Da

Reference Data

• Protein Families: Druggable Genome, Transcription Factors