Perilipin-1 (PLIN1) (C-term) Guinea Pig Polyclonal Antibody

CAT#: BP5033

Perilipin-1 (PLIN1) (C-term) guinea pig polyclonal antibody, Serum

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/2000 (ECL)
  Immunohistochemistry on Frozen Sections: 1/100-1/200 for 1 h at RT.
  Immunohistochemistry on Paraffin Sections: 1/100-1/200 for 1 h at RT. Microwave treatment required (for protocol cf. Straub et al. 2008).
  
  
• Reactivities: Bovine, Human
• Host: Guinea Pig
• Clonality: Polyclonal
• Immunogen: C-terminus of Perilipin-1 (hCTA/B; aa 507-519; cf. Greenberg et al. 1992, JBC 266, 11341-11346)
• Specificity: The antiserum reacts specifically with Perilipins located at the surface of intracellular storage lipid droplets present e.g. in the adrenal gland, adipocytes of white and brown adipose tissue and cultured cells such as 3T3-L1 adipocytes and cultured steroidogenic adrenal cortical and Leydig cells.
  The antiserum does not cross-react with Adipophilin (ADRP) or TIP47 proteins (additional members of the PAT-family).
• Formulation: State: Serum
  State: Liquid Stabilized Antiserum
  Preservative: 0.09% Sodium Azide
• Storage: Store undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens perilipin 1 (PLIN1), transcript variant 1
• Database Link:
  Entrez Gene 5346 Human
• Background: Perilipins build a family of phosphoproteins. The predominant forms in adipocytes, perilipin A and B arise by alternative RNA splicing from a single gene, generating polypeptides of 57 and 46 kD, respectively.
• Synonyms: Perilipin, PLIN, PLIN1, PLIN-1, PERI

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: PPAR signaling pathway