SYNPR Guinea Pig Polyclonal Antibody

CAT#: BP5104

SYNPR guinea pig polyclonal antibody, Serum

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Immunofluorescence Microscopy: 1/100-200 for 1 h at RT.
  Immunohistochemistry on Frozen Sections.
• Reactivities: Human, Mouse, Rat
• Host: Guinea Pig
• Clonality: Polyclonal
• Immunogen: Synthetic C-terminal peptide CHSSGQRYLSDPMEKHS (corresponding to a part of the cytoplasmic carboxy terminus) conjugated to KLH.
• Specificity: Antiserum reacts specifically with Synaptoporin present in synaptic vesicles.
  No cross-reaction with pantophysin and the closely related protein Synaptophysin (additional members of the small polypeptide family typical for transport vesicles).
• Formulation: State: Serum
  State: Liquid Serum
  Preservative: 0.09% Sodium Azide
• Gene Name: Homo sapiens synaptoporin (SYNPR), transcript variant 2
• Database Link:
  Entrez Gene 66030 RatEntrez Gene 72003 MouseEntrez Gene 132204 Human
• Background: SYNPR( Synaptoporin) is a component of the synaptic vesicle membrane and thought to play an important role in synaptic vesicle trafficking. It is highly homologous to Synaptophysin 1 yet it differs in expression. Synaptophysin 1 is ubiquitiously expressed, SYNPR is concentrated in the mossy fibre synapses of the hippocampus.
  Synaptoporin, an intrinsic membrane protein of small synaptic vesicles, probably functions as vesicular channel protein.
• Synonyms: MGC26651, Synaptophysin-2

Reference Data

• Protein Families: Secreted Protein, Transmembrane