Myosin light chain 3 (MYL3) Rabbit Polyclonal Antibody

CAT#: DP2015

Myosin light chain 3 (MYL3) rabbit polyclonal antibody, Aff - Purified

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant human myosin (cardiac) light chain fragment.
• Specificity: This antibody reacts to ventricular myosin light chain.
• Formulation: Azide Free, 0.05 M Phosphate buffer, 0.1 M NaCl, pH 7.2
  State: Aff - Purified
  State: Lyophilized purified IgG
  Preservative: None
• Reconstitution Method: Restore with 0.05 ml of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens myosin light chain 3 (MYL3)
• Database Link:
  Entrez Gene 4634 Human
• Background: Human ventricular myosin light chain (MLC-I, Essential Myosin Light Chain Isoform) is a 21 kDa cardiac contractile protein, which is one of component of myosin structure. The protein MLC-I is present in the contractile apparatus and not in cytosol. In severe congestive heart failure (CHF), myofibrils may degenerate and, subsequently, the myofibrillar components may be released into the circulation. The increased blood levels of MLC-I could indicate morphological changes in CHF, myocardial infarction, structural abnormalities in viable myocytes also observed in non-ischaemic CHF, myocardial necrosis.
• Synonyms: Myosin light chain 3, Myosin light chain 1, slow-twitch muscle B/ventricular isoform, MLC1SB, Cardiac myosin light chain 1, CMLC1
• Note: Quality Control Test
  Indirect ELISA - to determine titer of the antibody.
  SDS PAGE - to determine purity of the antibody.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)