CD13 (ANPEP) Mouse Monoclonal Antibody [Clone ID: WM15]

CAT#: SM1070AC

CD13 (ANPEP) mouse monoclonal antibody, clone WM15, APC


USD 300.00

2 Weeks*

Size
    • 100 Tests

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Specifications

Product Data
Clone Name WM15
Applications FC
Recommended Dilution Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension.
The content of a vial (1 ml) is sufficient for 100 tests.
Reactivities Human, Primate
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human AML cells
Specificity This antibody recognises the human CD13 cell surface glycoprotein, a 150 kDa molecule expressed on granulocytes, endothelial cells, epithelial cells and myeloid progenitors.
Formulation Phosphate buffered saline (PBS) containing 15 mM sodium azide
Label: APC
State: Liquid Ig fraction
Label: Conjugated with cross-linked Allophycocyanin under optimum conditions
Purification Size-exclusion chromatography
Conjugation APC
Storage Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens alanyl aminopeptidase, membrane (ANPEP)
Background CD13 (aminopeptidase N, APN) is a 150 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. This metalloprotease preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 has also role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas.
Synonyms Aminopeptidase N, ANPEP, APN, PEPN
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protease, Transmembrane
Protein Pathways Glutathione metabolism, Hematopoietic cell lineage, Metabolic pathways, Renin-angiotensin system

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.