Nkx3.1 (NKX3-1) Mouse Monoclonal Antibody

CAT#: TA301499

Mouse Monoclonal Antibody against NKX3.1

Product Images

Immunohistochemistry-Paraffin: NKX3.1 Antibody (0361) TA301499 - NKX3.1 was detected in immersion fixed paraffin-embedded sections of mouse testis using Mouse Anti-Mouse NKX3.1 (0361) Monoclonal Antibody (Catalog # TA301499) at 1:300 for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to the nuclei in sperm cells.

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  Western Blot: Nkx3.1 Antibody (0361) TA301499 - Detection of NKX3.1 in mouse testis lysate using NB 100-1828. ECL detection 1 minute.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Immunohistochemistry: 1:100, Immunoprecipitation: 1:10-1:500, Western Blot: 2 ug/ml, Immunohistochemistry-Paraffin: 1:100, Immunohistochemistry-Frozen: 1:100, Knockdown Validated
• Reactivities: Human, Mouse
• Host: Mouse
• Clonality: Monoclonal
• Immunogen: This antibody was raised against human Nkx3.1 full-length protein producced in bacteria as a hexahistidine-tagged protein.
• Formulation: PBS, pH 7.4 and 0.1% sodium azide
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: NK3 homeobox 1
• Database Link:
  NP_006158
  Entrez Gene 18095 MouseEntrez Gene 4824 Human
  UniProt ID Q99801
• Background: Nkx3.1 is a transcription factor that may play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in the prostate. It has been thought to be one of the target genes of the 8p21 loss of heterozygosity, common in prostate cancer. But neither disruption of the coding region of the gene, nor mutations have been found in prostate cancer.
• Synonyms: BAPX2; NKX3; NKX3.1; NKX3A

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Pathways in cancer, Prostate cancer