SWAP70 Rabbit Polyclonal Antibody

CAT#: TA302003

Rabbit Polyclonal Antibody against SWAP70 (Center)

Product Images

Western blot analysis of SWAP70 (arrow) using rabbit polyclonal SWAP70 Antibody (Center) (Cat# TA302003). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SWAP70 gene (Lane 2) (Origene Technologies).

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  Western blot analysis of anti-SWAP70 Antibody (Center) (Cat# TA302003) in HepG2 cell line lysates (35ug/lane). SWAP70 (arrow) was detected using the purified polyclonal antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This SWAP70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the Central region of human SWAP70.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 68998 Da
• Gene Name: SWAP switching B-cell complex 70kDa subunit
• Database Link:
  NP_055870
  Entrez Gene 20947 MouseEntrez Gene 23075 Human
  UniProt ID Q9UH65
• Background: SWAP70 is a phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. This protein regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
• Synonyms: HSPC321; SWAP-70