ATF 4 (ATF4) Rabbit Polyclonal Antibody

CAT#: TA302232

Rabbit Polyclonal Antibody against ATF4 (S245)


USD 450.00

In Stock*

Size
    • 100 ug

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 1:1000
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen This ATF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-252 amino acids from human ATF4.
Formulation Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 38459 Da
Gene Name activating transcription factor 4
Background ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). ATF4 belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain.
Synonyms CREB-2; CREB2; TAXREB67; TXREB
Reference Data
Protein Families Transcription Factors
Protein Pathways GnRH signaling pathway, Long-term potentiation, MAPK signaling pathway, Neurotrophin signaling pathway, Prostate cancer

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