UBTD1 Rabbit Polyclonal Antibody

CAT#: TA302267

Rabbit Polyclonal Antibody against UBTD1 (C-term G195)

Product Images

Western blot analysis of UBTD1 (arrow) using rabbit polyclonal UBTD1 Antibody (C-term G195) polyclonal antibody (Cat.#TA302267). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the UBTD1 gene (Lane 2) (Origene Technologies).

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  Western blot analysis of UBTD1 Antibody (C-term G195) (Cat.#TA302267) in Hl60 cell line lysates (35ug/lane). UBTD1 (arrow) was detected using the purified Pab.

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  Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with UBTD1 Antibody (C-term G195) (Cat.#TA302267), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000, IHC: 1:50
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This UBTD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-212 amino acids from the C-terminal region of human UBTD1.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25938 Da
• Gene Name: ubiquitin domain containing 1
• Database Link:
  NP_079230
  Entrez Gene 226122 MouseEntrez Gene 309373 RatEntrez Gene 80019 Human
  UniProt ID Q9HAC8
• Background: UBTD1 contains a ubiquitin domain, and has been demonstrated to bind to p53 in cells p53 is linked to the ubiquitination pathway through its transcriptional regulation of the four ubiquitin ligases, MDM2, COP1, Siah1b, and Pirh2. The role of UBTD1 has not been elucidated, however preliminary evidence indicates a potential role in p53 signaling.
• Synonyms: FLJ11807

Reference Data

• Protein Families: Druggable Genome