SMARCE1 Goat Polyclonal Antibody

CAT#: TA302426

Goat Polyclonal Antibody against BAF57 / SMARCE1

Product Images

A) HEK293 overexpressing BAF57 (RC209444) and probed with TA302426 (mock transfection in first lane), tested by Origene. B) Western blot of Jurkat cells

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  In paraffin embedded Human Prostate shows nuclear staining in secretory epithelial cells. Recommended concentration, 3-5ug/ml.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:16,000. WB: 0.2-0.6µg/ml.
• Reactivities: Human
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-PPTDPIPEDEKKE, from the C Terminus of the protein sequence according to NP_003070.3.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50276 Da
• Gene Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
• Database Link:
  NP_003070
  Entrez Gene 57376 MouseEntrez Gene 6605 Human
  UniProt ID Q969G3
• Background: The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq]
• Synonyms: BAF57; CSS5

Reference Data

• Protein Families: Transcription Factors