FOXN1 Goat Polyclonal Antibody

CAT#: TA302890

Goat Polyclonal Antibody against FOXN1

Product Images

TA302890 (20ug/ml) staining of paraffin embedded Human Thymus Medulla. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: ELISA: 1:32,000. WB: , 20-30µg/ml.
• Reactivities: Human
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-SVYLSPSSKPVALA, from the C Terminus of the protein sequence according to NP_003584.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: forkhead box N1
• Database Link:
  NP_003584
  Entrez Gene 8456 Human
  UniProt ID O15353
• Background: Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.
• Synonyms: FKHL20; RONU; WHN

Reference Data

• Protein Families: Druggable Genome, Transcription Factors