TLR9 Rabbit Polyclonal Antibody

CAT#: TA306290

Rabbit Polyclonal TLR9 Antibody


USD 430.00

3 Weeks*

Size
    • 100 ug

Product Images

Other products for "TLR9"

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 0.5 - 1 ug/mL, ICC: 2 ug/mL, IF: 10 ug/mL
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen TLR9 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human TLR9.
Formulation PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name toll like receptor 9
Background Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences (3) and are localized in intracellular acidic compartments such as the phagolysosome (4). Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection (5), TLR9 is strictly dependent on MyD88 (3).
Synonyms CD289
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Toll-like receptor signaling pathway

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.