FEZ2 Rabbit Polyclonal Antibody

CAT#: TA306503

Rabbit Polyclonal FEZ2 Antibody

Product Images

Western blot analysis of FEZ2 in mouse brain tissue lysate with FEZ2 antibody at (A) 0.5, and (B) 1 ug/mL.

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  Immunofluorescence of human brain tissue using FEZ25 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, IF: 5 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: FEZ2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human FEZ2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: fasciculation and elongation protein zeta 2
• Database Link:
  NP_001036013
  Entrez Gene 94269 RatEntrez Gene 225020 MouseEntrez Gene 9637 Human
  UniProt ID Q9UHY8
• Background: Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-z substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-z, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-z in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
• Synonyms: HUM3CL