MTCH2 Rabbit Polyclonal Antibody

CAT#: TA306737

Rabbit Polyclonal MTCH2 Antibody

Product Images

Western blot analysis of MTCH2 in 293 cell lysate with MTCH2 antibody at 1 ug/ml.

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  Immunohistochemistry of MTCH2 in mouse kidney tissue with MTCH2 antibody at 5 ug/ml.

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  Immunofluorescence of MTCH2 in Mouse Kidney cells with MTCH2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MTCH2 antibody was raised against a 15 amino acid peptide near the amino terminus of human MTCH2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: mitochondrial carrier 2
• Database Link:
  NP_055157
  Entrez Gene 23788 Human
  UniProt ID Q9Y6C9
• Background: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.
• Synonyms: HSPC032; MIMP; SLC25A50