Peroxiredoxin 6 (PRDX6) Rabbit Monoclonal Antibody [Clone ID: EPR3755]

CAT#: TA307267

Rabbit monoclonal antibody against Peroxiredoxin 6 (clone EPR3755 )

Product Images

Western blot - Peroxiredoxin 6 antibody [EPR3755]; All lanes : Anti-Peroxiredoxin 6 antibody [EPR3755] at 1/500 dilution.Lane 1 : HeLa cell lysate.Lane 2 : MCF-7 cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : A549 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 25 kDa.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Peroxiredoxin 6 antibody [EPR3755]; TA307267 at 1/100 dilution, staining Peroxiredoxin 6 in paraffin embedded Human brain tissue

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Peroxiredoxin 6 antibody [EPR3755] (TA307267); TA307267 showing positive staining in Normal breast tissue.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Peroxiredoxin 6 antibody [EPR3755] (TA307267); TA307267 showing positive staining in Normal liver tissue.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Peroxiredoxin 6 antibody [EPR3755] (TA307267); TA307267 showing positive staining in Normal colon tissue.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Peroxiredoxin 6 antibody [EPR3755] (TA307267); TA307267 showing positive staining in Normal kidney tissue.

• Immunocytochemistry/ Immunofluorescence - Peroxiredoxin 6 antibody [EPR3755]; TA307267, staining Peroxiredoxin 6 at 1/100 dilution in HeLa cells

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Specifications

Product Data

• Clone Name: EPR3755
• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1:500 - 1:1000; IP: 1:10; ICC/IF: 1:100 - 1:250
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues in human Peroxiredoxin 6 was used as an immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Purification: Tissue culture supernatant
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: peroxiredoxin 6
• Database Link:
  NP_004896
  Entrez Gene 11758 MouseEntrez Gene 94167 RatEntrez Gene 9588 Human
  UniProt ID P30041
• Background: Peroxiredoxin 6, a member of the thiol-specific antioxidant protein family (1), is an enzyme that detoxifies hydrogen peroxide and various organic peroxides (2). It is a cytosolic peroxidase that has been demonstrated to protect various tissues, such as skin, lung, and cardiac muscle, against acute oxidative insults (3). Peroxiredoxin 6 has two distinct active sites, and is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides (1). Peroxiredoxin 6 has been hypothesized to also protect the liver from oxidative stress generated during the process of chronic ethanol ingestion (3), and may play a role in the regulation of phospholipid turnover (1).
• Synonyms: 1-Cys; aiPLA2; AOP2; HEL-S-128m; NSGPx; p29; PRX
• Note: Is unsuitable for Flow Cyt.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Methane metabolism, Phenylalanine metabolism