BHMT Rabbit Polyclonal Antibody

CAT#: TA308187

Rabbit Polyclonal antibody to BHMT (betaine-homocysteine methyltransferase)

Product Images

Sample (30 ug whole cell lysate). A:Hep G2. 10% SDS PAGE. TA308187 diluted at 1:1000

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  BHMT antibody detects BHMT protein at cytosol on Colon Carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded Colon Carcinoma. BHMT antibody (TA308187) dilution: 1:500.

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  Immunofluorescence analysis of methanol-fixed A431, using BHMT (TA308187) antibody at 1:500 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 243 of BHMT (Uniprot ID#Q93088)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45 kDa
• Gene Name: betaine--homocysteine S-methyltransferase
• Database Link:
  NP_001704
  Entrez Gene 635 Human
  UniProt ID Q93088
• Background: This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq]
• Synonyms: BHMT1; HEL-S-61p

Reference Data

• Protein Pathways: Cysteine and methionine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways