CYP24A1 Rabbit Polyclonal Antibody

CAT#: TA308204

Rabbit polyclonal antibody to CYP24A1 (cytochrome P450, family 24, subfamily A, polypeptide 1)

Product Images

Sample (30ug whole cell lysate). A: 293T. B: A431. C: H1299. D: HeLa S3. E: Hep G2. F: MOLT4. G: Raji. 7.5% SDS PAGE. TA308204 diluted at 1:3000

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  Figure from citation: Western Blot of CYP24A1 protein level by using anti-CYP24A1 antibody in human thyroid cancer cell line. Dilution: 1:3000 View Citation

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  CYP24A1 antibody detects CYP24A1 protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. CYP24A1 antibody (TA308204) dilution: 1:500.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 241 and 514 of CYP24A1 (Uniprot ID#Q07973)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 59 kDa
• Gene Name: cytochrome P450 family 24 subfamily A member 1
• Database Link:
  NP_001122387
  Entrez Gene 13081 MouseEntrez Gene 25279 RatEntrez Gene 1591 Human
  UniProt ID Q07973
• Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: CP24; CYP24; HCAI; P450-CC24
• Note: Seq homology of immunogen across species: mouse (87%), Rat (88%)

Reference Data

• Protein Families: Druggable Genome