L Kynurenine Hydrolase (KYNU) Rabbit Polyclonal Antibody

CAT#: TA308219

Rabbit Polyclonal antibody to KYNU (kynureninase (L-kynurenine hydrolase))

Product Images

Sample (30 ug of whole cell lysate). A: A549. 10% SDS PAGE. TA308219 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded MCF7 xenograft, using KYNU (TA308219) antibody at 1:500 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 114 and 329 of KYNU (Uniprot ID#Q16719)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35 kDa
• Gene Name: kynureninase
• Database Link:
  NP_003928
  Entrez Gene 70789 MouseEntrez Gene 116682 RatEntrez Gene 8942 Human
  UniProt ID Q16719
• Background: Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: KYNUU
• Note: Seq homology of immunogen across species: Mouse (88%), Rat (88%), Bovine (89%)

Reference Data

• Protein Families: Protease
• Protein Pathways: Metabolic pathways, Tryptophan metabolism