TRPM2 Rabbit Polyclonal Antibody

CAT#: TA308572

Rabbit polyclonal antibody to TRPM2 (transient receptor potential cation channel, subfamily M, member 2)

Product Images

Sample (30 ug of whole cell lysate). A: Hep G2. 7.5% SDS PAGE. TA308572 diluted at 1:500.

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  Immunohistochemical analysis of paraffin-embedded MDAMB468 xenograft, using TRPM2 (TA308572) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 181 and 423 of TRPM2 (Uniprot ID#O94759)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 171 kDa
• Gene Name: transient receptor potential cation channel subfamily M member 2
• Database Link:
  NP_003298
  Entrez Gene 28240 MouseEntrez Gene 294329 RatEntrez Gene 7226 Human
  UniProt ID O94759
• Background: The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq]
• Synonyms: EREG1; KNP3; LTRPC2; NUDT9H; NUDT9L1; TRPC7
• Note: Seq homology of immunogen across species: mouse (90%), Rat (90%)

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane