NOVA1 Rabbit Polyclonal Antibody

CAT#: TA308650

Rabbit polyclonal antibody to NOVA1 (neuro-oncological ventral antigen 1)

Product Images

Sample (30 ug of whole cell lysate). A: PC-3. 10% SDS PAGE. TA308650 diluted at 1:1000.

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  Immunofluorescence analysis of paraformaldehyde-fixed A431, using NOVA1 (TA308650) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment contain a sequence corresponding to a region within amino acids 315 and 510 of NOVA1
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 52 kDa
• Gene Name: NOVA alternative splicing regulator 1
• Database Link:
  NP_006482
  Entrez Gene 4857 Human
  UniProt ID P51513
• Background: This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq]
• Synonyms: Nova-1
• Note: Seq homology of immunogen across species: Xenopus laevis (95%)