MURF1 (TRIM63) Rabbit Polyclonal Antibody

CAT#: TA308746

Rabbit Polyclonal antibody to MURF1 (tripartite motif-containing 63)

Product Images

Sample (30 ug whole cell lysate). A:Hep G2. 10% SDS PAGE. TA308746 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded Breast ca, using MURF1 (TA308746) antibody at 1:500 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using MURF1 (TA308746) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 44 of MURF1 (Uniprot ID#Q969Q1)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40 kDa
• Gene Name: tripartite motif containing 63
• Database Link:
  NP_115977
  Entrez Gene 84676 Human
  UniProt ID Q969Q1
• Background: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq]
• Synonyms: IRF; MURF1; MURF2; RNF28; SMRZ
• Note: Seq homology of immunogen across species: Pig (100%), Rhesus Monkey (100%), Bovine (100%)