Ubiquilin (UBQLN1) Rabbit Polyclonal Antibody

CAT#: TA308768

Rabbit polyclonal antibody to Ubiquilin-1 (ubiquilin 1)


USD 415.00

5 Days*

Size
    • 100 ul

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Specifications

Product Data
Applications IF, WB
Recommended Dilution ICC/IF:1:100-1:1000; WB:1:500-1:3000
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 64 and 345 of Ubiquilin-1 (Uniprot ID#Q9UMX0)
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 63 kDa
Gene Name ubiquilin 1
Background This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms DA41; DSK2; PLIC-1; UBQN; XDRP1
Note Seq homology of immunogen across species: Mouse (90%), Rat (90%), Bovine (95%)
Reference Data
Protein Families Druggable Genome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.