Frequenin (NCS1) Rabbit Polyclonal Antibody

CAT#: TA309002

Rabbit Polyclonal antibody to NCS1 (neuronal calcium sensor 1)

Product Images

Sample (30 ug of whole cell lysate). A:A431. B:Hep G2. 12% SDS PAGE. TA309002 diluted at 1:200

• 

  NCS1 antibody detects NCS1 protein at on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. NCS1 antibody (TA309002) dilution: 1:500.

• 

  Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed A431, using NCS1 (TA309002) antibody (Green) at 1:100 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:500.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:100-1:1000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 138 of NCS1
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 22 kDa
• Gene Name: neuronal calcium sensor 1
• Database Link:
  NP_001122298
  Entrez Gene 14299 MouseEntrez Gene 23413 Human
  UniProt ID P62166
• Background: This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: FLUP; FREQ
• Note: Seq homology of immunogen across species: Mouse (100%), Xenopus laevis (99%), Bovine (99%), Xenopus tropicalis (100%)

Reference Data

• Protein Families: Druggable Genome