FTO Mouse Monoclonal Antibody [Clone ID: 5-2H10]

CAT#: TA309122

Mouse Anti-FTO ( Fat mass and obesity related protein) Antibody

Product Images

Western blot of rat testes lysate showing specific immunolabeling of the ~ 58k Fto protein.

Specifications

Product Data

• Clone Name: 5-2H10
• Applications: WB
• Recommended Dilution: WB: 1:1,000, IF: 1:100
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
• Formulation: 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 58 kDa
• Gene Name: fat mass and obesity associated
• Database Link:
  NP_001073901
  Entrez Gene 26383 MouseEntrez Gene 291905 RatEntrez Gene 79068 Human
  UniProt ID Q9C0B1
• Background: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq]
• Synonyms: ALKBH9; BMIQ14; GDFD