Calpain 1 (CAPN1) Rabbit Polyclonal Antibody

CAT#: TA318876

Rabbit polyclonal anti-Calpain 1 antibody

Product Images

Western blot analysis of Calpain 1 expression in lysate from Jurkat cells treated with (Lane 2) or without (Lane 1) camptothecin.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4ug/ml
• Reactivities: Bovine, Human, Mouse, Rabbit, Rat, Pig
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 700 of rat Calpain 1
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-calpain I (large subunit) antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: calpain 1
• Database Link:
  NP_001185797
  Entrez Gene 12333 MouseEntrez Gene 29153 RatEntrez Gene 823 Human
  UniProt ID P07384
• Background: Calpains are cytosolic, calcium-dependent, cysteine proteases that are ubiquitously expressed in mammalian and avian tissues. Type I calpain requires micromolar amounts of calcium, while type II calpain requires millimolar amounts of calcium. The anti-calpain I antibody recognizes the large subunit (80 kDa) of human Calpain I. It does not recognize the smaller subunit of human Calpain I.
• Synonyms: CANP; CANP1; CANPL1; muCANP; muCL; SPG76

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Alzheimer's disease, Apoptosis