Factor D (CFD) Rabbit Polyclonal Antibody

CAT#: TA319009

Rabbit polyclonal anti-CFD (Adipsin) antibody

Product Images

Western blot analysis of Adipsin with rat kidney tissue lysate.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 232 of mouse Adipsin
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: complement factor D
• Database Link:
  NP_001919
  Entrez Gene 11537 MouseEntrez Gene 54249 Rat
  UniProt ID P00746
• Background: Adipsin is a serine protease secreted by adipose tissue, and it has also been found in monocytes/macrophages. Adipsin has been identified to be similar to complement Factor D. Adipsin cleaved complement Factor B when the later form complexed with activated complement component C3. Low level expression of Adipsin has been linked to obesity in mouse model suggesting that defects in Adipsin is the result of this systemic disorder.
• Synonyms: ADIPSIN; ADN; DF; PFD

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Complement and coagulation cascades