GRO alpha (CXCL1) Rabbit Polyclonal Antibody

CAT#: TA319046

Rabbit polyclonal anti-CXCL1 (KC) antibody

Product Images

Western blot analysis of KC in lysates from Jurkat cells (Lane 1) and 3T3 cells (Lane 2).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 78 of mouse KC
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: C-X-C motif chemokine ligand 1
• Database Link:
  NP_001502
  Entrez Gene 14825 MouseEntrez Gene 81503 RatEntrez Gene 2919 Human
  UniProt ID P09341
• Background: KC, a homolog of human and hamster gro/MGSA, is a 72-amino acid CXC chemokine originally cloned from rat macrophages and lung tissue. It is the mediator for recruitment and activation of neutrophils in rat lung inflammation models. Expression of KC can be upregulated by LPS and IL-1-gamma stimulation. IFN-g blocks LPS-induced expression of KC.
• Synonyms: FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway