iASPP (PPP1R13L) Rabbit Polyclonal Antibody

CAT#: TA319363

Rabbit polyclonal anti-iASSP antibody


USD 530.00

5 Days*

Size
    • 100 ug

Product Images

Other products for "PPP1R13L"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA: 1:40,000 - 1:160,000, WB: 1:1,000 - 1:5,000, IHC: 1:1,000 - 1:5,000
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 780-797 of human iASPP (isoform 1) protein.
Formulation 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration lot specific
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name protein phosphatase 1 regulatory subunit 13 like
Synonyms IASPP; NKIP1; RAI; RAI4
Note ASPP proteins (ASPP1, ASPP2 and iASPP) represent a new family of p53 binding proteins. ASPP1 and ASPP2 bind and enhance p53-mediated apoptosis. In contrast, the third member, iASPP, functionally inactivates p53. iASPP (also called protein phosphatase 1 regulatory (inhibitor) subunit 13 like protein, Inhibitor of ASPP protein, Protein iASPP, PPP1R13B-like protein and NFkB-interacting protein 1) plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. iASPP blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1.
Reference Data
Protein Families Transcription Factors

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.