HOX11 (TLX1) Rabbit Polyclonal Antibody

CAT#: TA319661

Rabbit Polyclonal TLX1 Antibody

Product Images

Western blot analysis of TLX1 in mouse spleen tissue lysate with TLX1 antibody at (A) 1 ug/mL and (B) 2 ug/mL.

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  Immunohistochemistry of TLX1 in human spleen tissue with TLX1 antibody at 2.5 ug/mL.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TLX1 antibody was raised against a 16 amino acid peptide near the amino terminus of human TLX1.
• Formulation: TLX1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TLX1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 36 kDa; Observed: 35 kDa
• Gene Name: T-cell leukemia homeobox 1
• Database Link:
  NP_005512
  Entrez Gene 21908 MouseEntrez Gene 499361 RatEntrez Gene 3195 Human
  UniProt ID P31314
• Background: TLX1 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.
• Synonyms: HOX11; TCL3