SYBL1 (VAMP7) Rabbit Polyclonal Antibody

CAT#: TA319712

Rabbit Polyclonal VAMP7 Antibody

Product Images

Western blot analysis of VAMP7 in mouse lung tissue lysate with VAMP7 antibody at 1 ug/mL.

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  Immunofluorescence of VAMP7 in human lung tissue with VAMP7 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: VAMP7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human VAMP7.
• Formulation: VAMP7 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: VAMP7 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: vesicle associated membrane protein 7
• Database Link:
  NP_005629
  Entrez Gene 20955 MouseEntrez Gene 85491 RatEntrez Gene 6845 Human
  UniProt ID P51809
• Background: VAMP7 Antibody: VAMP7 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family, localizing to late endosomes and lysosomes. VAMP7 is thought to mediate the fusion of endosomes to their target lysosomes as well as other exocytosis events during phagocytosis and neuritogenesis. VAMP7 interacts with the VPS9 ankyrin repeat protein VARP, a protein that localizes to early endosomes and thought to regulate endosome dynamics. Together with CD82, VAMP7 can modulate the signaling of EGFR by regulating its endocytosis from the plasma membrane.
• Synonyms: SYBL1; TI-VAMP; TIVAMP; VAMP-7

Reference Data

• Protein Families: Transcription Factors, Transmembrane
• Protein Pathways: SNARE interactions in vesicular transport